exRNAdisease

Entry Detail

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General Information

Database ID: exR0428797 RNA Name: ACSF2 RNA Type: mRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 50426158 End Site(bp): 50474845 External Links: ENSG00000167107

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC006030.1 chr2 74211604 74363377 - AP4E1 chr15 50908672 51005895 + ARF5 chr7 127588386 127591700 + C11orf49 chr11 46936689 47164385 + COX10 chr17 14069490 14231736 + CPNE5 chr6 36740775 36839444 - DCTN1 chr2 74361154 74392087 - EIF4B chr12 53006158 53042209 + FSCN3 chr7 127591409 127602144 + GGA2 chr16 23463542 23521995 - GSTP1 chr11 67583742 67586656 + HSPA9 chr5 138553756 138575416 - IARS2 chr1 220094132 220148041 + MEF2A chr15 99565417 99716466 + PARP1 chr1 226360691 226408093 - PIP5K1A chr1 151197949 151249536 + RPL3 chr22 39312882 39320389 - RPS12 chr6 132814569 132817564 + SCOC chr4 140257286 140385726 + SEMA6B chr19 4542593 4559684 - TMBIM6 chr12 49707725 49764934 + UBA2 chr19 34428352 34471251 + UBE2A chrX 119574536 119591083 + YPEL3 chr16 30092314 30096915 - ZNF219 chr14 21090077 21104722 - ZNF785 chr16 30573740 30585769 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand CCDC144NL-AS1 chr17 20868433 21002276 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.