exRNAdisease

Entry Detail

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General Information

Database ID: exR0428798 RNA Name: ACSF3 RNA Type: mRNA Chromosome: chr16 Starnd: + Coordinate: Start Site(bp): 89088375 End Site(bp): 89164121 External Links: ENSG00000176715

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand REXO1 chr19 1815248 1848483 - PBX1 chr1 164555584 164899296 + RBFOX2 chr22 35738736 36028824 - FAM193B chr5 177519789 177554563 - SLC47A1 chr17 19495385 19579034 + ATG2A chr11 64894546 64917211 - TP63 chr3 189631389 189897276 + ARID1A chr1 26693236 26782104 + SBNO2 chr19 1107637 1174268 - AKT2 chr19 40230317 40285536 - LRRC14 chr8 144517992 144525172 + DGKD chr2 233354507 233472104 + SATB1 chr3 18345377 18445588 - DCTD chr4 182890060 182917936 - NHSL1 chr6 138422043 138692571 - SOX4 chr6 21593751 21598619 + ZNF227 chr19 44207547 44237268 + FAM189B chr1 155247205 155255483 - PAK4 chr19 39125770 39182816 + SNRPB chr20 2461634 2470853 - RPL18A chr19 17859910 17864153 + NDUFV2 chr18 9102630 9134345 + ABR chr17 1003518 1229738 - TANGO2 chr22 20017014 20067164 + BPTF chr17 67825503 67984378 + UBA52 chr19 18571730 18577550 + SYAP1 chrX 16719612 16765340 + ADAR chr1 154582057 154628013 - TXNL1 chr18 56597209 56651600 - NUP153 chr6 17615035 17706834 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AP005263.1 chr18 9102736 9254346 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.