exRNAdisease

Entry Detail

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General Information

Database ID: exR0428800 RNA Name: ACSL3 RNA Type: mRNA Chromosome: chr2 Starnd: + Coordinate: Start Site(bp): 222860942 End Site(bp): 222944639 External Links: ENSG00000123983

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand BCORL1 chrX 129981107 130058083 + GANAB chr11 62624826 62646726 - TMA7 chr3 48440257 48444208 + TPMT chr6 18128311 18155077 - EIF1B chr3 40309707 40312424 + AIFM1 chrX 130129362 130165887 - IRX3 chr16 54283304 54286787 - OTUD1 chr10 23439458 23442390 + VASN chr16 4371848 4383538 + TTC37 chr5 95461755 95555007 - EP300 chr22 41092592 41180077 + NSUN4 chr1 46340177 46365152 + MED1 chr17 39404285 39451272 - MAGT1 chrX 77826364 77895593 - EEF2 chr19 3976056 3985463 - ZWILCH chr15 66504959 66550130 + RPL7L1 chr6 42879616 42889925 + AP001781.2 chr11 111786286 111879425 - RPS7 chr2 3575260 3580920 + TUBA1A chr12 49184795 49189080 - SMARCC1 chr3 47585269 47782106 - DDX39B chr6 31530219 31542448 - IQSEC1 chr3 12897043 13283281 - DBN1 chr5 177456608 177474401 - MRFAP1 chr4 6640091 6642745 + ISCA1 chr9 86264546 86283102 - GNA12 chr7 2728105 2844308 - INTS13 chr12 26905181 26938326 - DMXL2 chr15 51447711 51622833 - CD47 chr3 108043091 108091862 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010733.2 chr2 60925909 60931610 + AC245033.2 chr15 82540870 82562374 + LINC00836 chr10 25651712 25732935 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.