exRNAdisease

Entry Detail

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General Information

Database ID: exR0428801 RNA Name: ACSL4 RNA Type: mRNA Chromosome: chrX Starnd: - Coordinate: Start Site(bp): 109624244 End Site(bp): 109733403 External Links: ENSG00000068366

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CEP78 chr9 78236062 78279690 + RPL23 chr17 38847860 38853764 - ADGRL1 chr19 14147743 14206187 - LRBA chr4 150264435 151015727 - ACOT2 chr14 73567620 73575658 + COX8A chr11 63974620 63976543 + PITPNC1 chr17 67377281 67697261 + BEX5 chrX 102153708 102155977 - NUDT21 chr16 56429133 56452199 - NUCKS1 chr1 205712822 205750182 - BHLHE40 chr3 4979437 4985323 + ZMYM4 chr1 35268709 35422058 + KCNE5 chrX 109623700 109625172 - C9orf40 chr9 74946583 74952912 - CPZ chr4 8592660 8619759 + MZT2A chr2 131464900 131492743 - ENO1 chr1 8861000 8879190 - ARPC5 chr1 183620846 183635783 - ZMAT2 chr5 140698680 140706686 + MKNK2 chr19 2037465 2051244 - MTRNR2L1 chr17 22523111 22524663 + HELQ chr4 83407343 83455855 - GAPDH chr12 6534512 6538374 + FOXRED1 chr11 126269055 126278131 + KRAS chr12 25205246 25250936 - TIMM17B chrX 48893447 48898143 - COPB2 chr3 139355600 139389680 - UBL7 chr15 74445977 74461182 - CDS2 chr20 5126879 5197887 + EFTUD2 chr17 44849948 44899445 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-34a-5p chr1 9151735 9151756 - hsa-miR-34c-5p chr11 111513451 111513473 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC106864.1 chr4 112693047 112706810 - AL117378.1 chr6 131901963 131920565 + AP003175.1 chr11 75069243 75096964 - NEAT1 chr11 65422774 65445540 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.