exRNAdisease

Entry Detail

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General Information

Database ID: exR0428809 RNA Name: ACSS1 RNA Type: mRNA Chromosome: chr20 Starnd: - Coordinate: Start Site(bp): 25006230 End Site(bp): 25058980 External Links: ENSG00000154930

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CTSB chr8 11842524 11869448 - RPL13 chr16 89560657 89566828 + RPL3 chr22 39312882 39320389 - MX1 chr21 41420304 41459214 + MKI67 chr10 128096659 128126423 - PTK2B chr8 27311482 27459391 + CLPTM1L chr5 1317752 1345099 - DIMT1 chr5 62347284 62403939 - LCP1 chr13 46125920 46211871 - CD79A chr19 41877279 41881372 + CMC4 chrX 155061622 155071136 - PHC3 chr3 170086732 170181749 - SASH3 chrX 129779949 129795201 + PAICS chr4 56435741 56464579 + PGM2 chr4 37826660 37862937 + MTRNR2L8 chr11 10507894 10509186 - AC092073.1 chr19 34396315 34409364 + ARL6IP6 chr2 152717893 152761253 + RPS29 chr14 49570984 49599164 - MTCP1 chrX 155064034 155147937 - GPI chr19 34359480 34402413 + CASP8 chr2 201233443 201287711 + MSL3 chrX 11758159 11775772 + EEF2 chr19 3976056 3985463 - SFPQ chr1 35176378 35193145 - TNFRSF14 chr1 2555639 2565382 + ACAD8 chr11 134253495 134265855 + RPL14 chr3 40457292 40468587 + PPP2R1A chr19 52190048 52229518 + SYVN1 chr11 65121780 65134533 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.