exRNAdisease

Entry Detail

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General Information

Database ID: exR0428810 RNA Name: ACSS2 RNA Type: mRNA Chromosome: chr20 Starnd: + Coordinate: Start Site(bp): 34872146 End Site(bp): 34927962 External Links: ENSG00000131069

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RPS19 chr19 41860255 41872925 + TUBA1B chr12 49127782 49131397 - VPS26B chr11 134224671 134247788 + EIF6 chr20 35278911 35284985 - KIAA0930 chr22 45190338 45240769 - KLHDC4 chr16 87696485 87765992 - TXNL4A chr18 79970813 80033949 - TUBA1A chr12 49184795 49189080 - NDUFB1 chr14 92116122 92121917 - DUT chr15 48331011 48343373 + NUCKS1 chr1 205712822 205750182 - SIK3 chr11 116843402 117098437 - COPS7B chr2 231781671 231809254 + LMBR1 chr7 156668946 156893216 - PFN1 chr17 4945652 4949061 - SLC52A3 chr20 760080 776015 - BLOC1S4 chr4 6716174 6717664 + GDI2 chr10 5765223 5842132 - DDX5 chr17 64498254 64508199 - TPI1 chr12 6867119 6870948 + KXD1 chr19 18557762 18569387 + NDUFS7 chr19 1383527 1395589 + DPF2 chr11 65333852 65354262 + AL121753.1 chr20 35267885 35280043 - STAT5B chr17 42199177 42276707 - RPS11 chr19 49496365 49499708 + DYNLL1 chr12 120469850 120498493 + PPP6R1 chr19 55229779 55259017 - STAU1 chr20 49113339 49188367 - HSP90AB1 chr6 44246166 44253888 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-18a-5p chr13 91350756 91350778 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL022311.1 chr22 37876148 37895563 + AL022332.1 chr22 25279529 25282674 - GAS5 chr1 173858559 173868882 - LINC01405 chr12 110934590 110959093 + MIR17HG chr13 91347820 91354579 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.