exRNAdisease

Entry Detail

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General Information

Database ID: exR0428823 RNA Name: ACTR10 RNA Type: mRNA Chromosome: chr14 Starnd: + Coordinate: Start Site(bp): 58200080 End Site(bp): 58235636 External Links: ENSG00000131966

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand HIBCH chr2 190189735 190344193 - CCNG1 chr5 163437569 163446151 + PPP2CA chr5 134194332 134226073 - TOMM20 chr1 235109341 235128837 - ACTB chr7 5527148 5563784 - APP chr21 25880550 26171128 - PTK2B chr8 27311482 27459391 + CTDSP2 chr12 57819927 57846729 - SLC6A9 chr1 43991500 44031467 - B2M chr15 44711487 44718877 + RPS20 chr8 56067295 56074581 - NUDC chr1 26900238 26946871 + AURKA chr20 56369389 56392337 - PABPC3 chr13 25095868 25099254 + TUBA3C chr13 19173772 19181824 - UBA6 chr4 67612652 67701155 - CAND1 chr12 67269358 67319953 + MGRN1 chr16 4616493 4690974 + ARF1 chr1 228082660 228099212 + ALDOA chr16 30064164 30070457 + MTRNR2L12 chr3 96617188 96618236 - PBX1 chr1 164555584 164899296 + PRKCI chr3 170222424 170305977 + LRRC20 chr10 70298970 70382650 - CCNC chr6 99542387 99568825 - SMARCC1 chr3 47585269 47782106 - TSPAN15 chr10 69451465 69507666 + NID1 chr1 235975830 236065109 - CAMK2G chr10 73812501 73874591 - AIF1L chr9 131096476 131123152 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.