exRNAdisease

Entry Detail

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General Information

Database ID: exR0428824 RNA Name: ACTR1A RNA Type: mRNA Chromosome: chr10 Starnd: - Coordinate: Start Site(bp): 102461881 End Site(bp): 102502712 External Links: ENSG00000138107

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACTR1B chr2 97655939 97664044 - AP002990.1 chr11 62559603 62591531 - PPP3R1 chr2 68178857 68256237 - MT-ND3 chrMT 10059 10404 + CDK19 chr6 110609978 110815958 - ERC2 chr3 55508311 56468467 - MT-ND1 chrMT 3307 4262 + INO80 chr15 40978880 41116280 - TCOF1 chr5 150357629 150400308 + OS9 chr12 57693955 57721557 + GOLGA7 chr8 41490396 41510980 + PAPOLA chr14 96501433 96567111 + IGFBP2 chr2 216632828 216664436 + RPL27A chr11 8682788 8714759 + PDE7A chr8 65717510 65842322 - RPS6 chr9 19375715 19380236 - HNRNPL chr19 38836388 38852347 - MT-ND4 chrMT 10760 12137 + EIF5AL1 chr10 79512601 79516440 + COMMD10 chr5 116085016 116412762 + TMSB4X chrX 12975110 12977227 + RPL29 chr3 51993522 51995895 - CBSL chr21 6444869 6468040 - GGCT chr7 30496621 30504841 - ARHGEF19 chr1 16197854 16212652 - SAE1 chr19 47113274 47210636 + TRIM28 chr19 58544064 58550722 + CHST14 chr15 40470998 40474571 + TBCB chr19 36114289 36125947 + CREBL2 chr12 12611827 12645108 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-363-3p chrX 134169382 134169403 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC011297.1 chrY 6918682 6920791 + AC027020.2 chr15 100547765 100550153 - AC245014.3 chr1 145281116 145281462 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.