exRNAdisease

Entry Detail

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General Information

Database ID: exR0428825 RNA Name: ACTR1B RNA Type: mRNA Chromosome: chr2 Starnd: - Coordinate: Start Site(bp): 97655939 End Site(bp): 97664044 External Links: ENSG00000115073

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand TEDC2 chr16 2460086 2464963 + COMMD1 chr2 61888724 62147247 + SDC2 chr8 96493813 96611790 + SND1 chr7 127652194 128092609 + RAB11A chr15 65726054 65891989 + ACTG1 chr17 81509971 81523847 - PCBP1 chr2 70087477 70089203 + WRAP73 chr1 3630767 3652761 - ACTA1 chr1 229431245 229434098 - SNURF chr15 24954986 24977850 + PIK3C2B chr1 204422628 204494724 - KEAP1 chr19 10486125 10503558 - GAPDH chr12 6534512 6538374 + GSTP1 chr11 67583742 67586656 + POTEE chr2 131218067 131265278 + KCTD2 chr17 75032575 75065889 + YLPM1 chr14 74763316 74859435 + MTRNR2L12 chr3 96617188 96618236 - MFSD2B chr2 24010081 24063321 + PGAM1 chr10 97426191 97433444 + BAG6 chr6 31639028 31652705 - PTMA chr2 231706895 231713541 + PSMB1 chr6 170535120 170553307 - PLXNB2 chr22 50274979 50307646 - RPN1 chr3 128619969 128681075 - ZNF106 chr15 42412823 42491141 - CLNS1A chr11 77514936 77637794 - ABLIM1 chr10 114431113 114768061 - AL136295.5 chr14 24147548 24166452 + EWSR1 chr22 29268009 29300525 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008555.1 chr19 34811589 34814345 - AL021707.2 chr22 38667585 38681847 - AL355075.4 chr14 20343048 20343685 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.