exRNAdisease

Entry Detail

---



General Information

Database ID: exR0428827 RNA Name: ACTR3 RNA Type: mRNA Chromosome: chr2 Starnd: + Coordinate: Start Site(bp): 113890063 End Site(bp): 113962596 External Links: ENSG00000115091

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CD53 chr1 110871188 110899922 + PTPRCAP chr11 67435510 67437682 - GLI1 chr12 57459785 57472268 + MT-ATP6 chrMT 8527 9207 + EZR chr6 158765741 158819368 - PGRMC2 chr4 128269237 128288829 - RPL11 chr1 23691742 23696835 + TRIM27 chr6 28903002 28923988 - RPL4 chr15 66498015 66524532 - TEAD3 chr6 35473597 35497079 - ERLIN1 chr10 100150094 100186033 - SF3A1 chr22 30331988 30356919 - MARS2 chr2 197705369 197708395 + AC245033.1 chr15 82536788 82573194 - CENPI chrX 101098218 101163681 + ERG28 chr14 75649791 75660876 - PSMD8 chr19 38374536 38383824 + NUMA1 chr11 72002864 72080693 - DSTN chr20 17570075 17609919 + UBE2D3 chr4 102794383 102868896 - TSPAN33 chr7 129144707 129169699 + RPS29 chr14 49570984 49599164 - DDB1 chr11 61299451 61342596 - ERGIC3 chr20 35542021 35557634 + CCT8 chr21 29055805 29073797 - MLXIPL chr7 73593194 73624543 - HLA-DRB5 chr6 32517353 32530287 - PCBP2 chr12 53452102 53481162 + MEX3A chr1 156072013 156082465 - ATPAF1 chr1 46632737 46673867 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC023509.1 chr12 53441741 53467528 + AC245033.4 chr15 82533175 82540008 - AL035458.2 chr20 34234840 34281173 - AC093734.1 chr7 1508655 1509427 - GAS5 chr1 173858559 173868882 - MALAT1 chr11 65497688 65506516 + TMEM147-AS1 chr19 35540738 35546029 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.