exRNAdisease

Entry Detail

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General Information

Database ID: exR0428828 RNA Name: ACTR3B RNA Type: mRNA Chromosome: chr7 Starnd: + Coordinate: Start Site(bp): 152759749 End Site(bp): 152855378 External Links: ENSG00000133627

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ASH1L chr1 155335268 155562807 - RPL27A chr11 8682788 8714759 + AC010422.3 chr19 12643831 12648397 - CNIH4 chr1 224356858 224379459 + GAB2 chr11 78215293 78418348 - POU5F1 chr6 31164337 31180731 - SPOUT1 chr9 128819651 128829794 - RNF40 chr16 30761745 30776307 + TRIM14 chr9 98069275 98119222 - EEF2 chr19 3976056 3985463 - IPO7 chr11 9384652 9448127 + RPS12 chr6 132814569 132817564 + TRIM26 chr6 30184455 30213427 - SLC25A37 chr8 23528956 23575463 + HSP90AB1 chr6 44246166 44253888 + DAXX chr6 33318558 33323016 - PLS3 chrX 115561174 115650861 + MTFR2 chr6 136231024 136250335 - GSTK1 chr7 143244093 143270854 + SLC39A1 chr1 153959099 153968184 - EIF5A chr17 7306999 7312463 + SRSF4 chr1 29147743 29181900 - EIF5B chr2 99337371 99401326 + UBR5 chr8 102252273 102412759 - ZNF638 chr2 71276561 71435069 + STX7 chr6 132445867 132513198 - ALG10B chr12 38316762 38329721 + INCENP chr11 62123998 62153169 + EIF3L chr22 37848868 37889407 + RBBP7 chrX 16839283 16870414 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL022311.1 chr22 37876148 37895563 + LINC00963 chr9 129476946 129513687 + LINC01315 chr22 42364390 42369284 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.