exRNAdisease

Entry Detail

---



General Information

Database ID: exR0428830 RNA Name: ACTR5 RNA Type: mRNA Chromosome: chr20 Starnd: + Coordinate: Start Site(bp): 38748460 End Site(bp): 38772520 External Links: ENSG00000101442

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ATP5PF chr21 25716503 25735673 - DPP3 chr11 66480013 66509657 + FUS chr16 31180110 31194871 + HNRNPA1 chr12 54280193 54287088 + IGF2 chr11 2129112 2141238 - MATR3 chr5 139273752 139331671 + MBTPS2 chrX 21839617 21885423 + NDUFA4 chr7 10931943 10940153 - OS9 chr12 57693955 57721557 + RAB1B chr11 66268590 66277492 + RAN chr12 130872037 130877678 + RPL8 chr8 144789765 144792587 - RPLP0 chr12 120196699 120201235 - SLC3A2 chr11 62856102 62888875 + STMN1 chr1 25884181 25906991 - TATDN1 chr8 124488485 124539458 - USP3 chr15 63504511 63594640 + ZNF618 chr9 113876282 114056591 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AP000233.2 chr21 25095022 25103670 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.