exRNAdisease

Entry Detail

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General Information

Database ID: exR0428831 RNA Name: ACTR6 RNA Type: mRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 100199122 End Site(bp): 100241865 External Links: ENSG00000075089

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ANKFY1 chr17 4163821 4263995 - DDX24 chr14 94048287 94081212 - AP002990.1 chr11 62559603 62591531 - CD52 chr1 26317958 26320523 + HNRNPC chr14 21209136 21269494 - RPS23 chr5 82273320 82278396 - NAGK chr2 71064344 71079808 + EEF1G chr11 62559596 62574086 - RPL13 chr16 89560657 89566828 + IGF2 chr11 2129112 2141238 - UBE2D3 chr4 102794383 102868896 - CD81 chr11 2376177 2397419 + VSIG10 chr12 118063593 118136026 - TMEM123 chr11 102396332 102470384 - ACTB chr7 5527148 5563784 - GYG2 chrX 2828822 2882820 + RAB35 chr12 120095099 120117502 - NSUN5 chr7 73302516 73308826 - HLA-C chr6 31268749 31272130 - ATP6AP2 chrX 40579372 40606848 + FTH1 chr11 61959718 61967634 - MTRNR2L12 chr3 96617188 96618236 - ADH5 chr4 99070978 99088801 - CLEC2D chr12 9664969 9699553 + NONO chrX 71283192 71301168 + RPS7 chr2 3575260 3580920 + ZNF90 chr19 20077994 20127076 + SLAMF1 chr1 160608106 160647295 - ST8SIA1 chr12 22063773 22437041 - YIPF3 chr6 43511832 43516985 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-6747-3p chr11 62567011 62567031 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand LINC02539 chr6 137730170 137792835 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.