exRNAdisease

Entry Detail

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General Information

Database ID: exR0428832 RNA Name: ACTR8 RNA Type: mRNA Chromosome: chr3 Starnd: - Coordinate: Start Site(bp): 53867066 End Site(bp): 53882152 External Links: ENSG00000113812

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RNF167 chr17 4940008 4945222 + ZDHHC4 chr7 6577434 6589374 + UTP6 chr17 31860904 31901708 - VMP1 chr17 59707192 59842255 + XPO5 chr6 43522334 43576038 - WFS1 chr4 6269849 6303265 + MT-ATP6 chrMT 8527 9207 + FTL chr19 48965309 48966879 + CHPT1 chr12 101696947 101744140 + EDARADD chr1 236348257 236502915 + PAICS chr4 56435741 56464579 + DENND4B chr1 153929501 153946718 - EIF1AX chrX 20124525 20141838 - CLTB chr5 176392455 176416569 - HLA-E chr6 30489509 30494194 + LSM12 chr17 44034328 44067619 - IGF2BP1 chr17 48997385 49056145 + TRAP1 chr16 3651639 3717553 - CD81 chr11 2376177 2397419 + OAZ1 chr19 2269509 2273490 + QPRT chr16 29663279 29698699 + MYO9B chr19 17075781 17214537 + DCAF15 chr19 13952492 13961449 + HLA-B chr6 31269491 31357188 - ACTN4 chr19 38647649 38731589 + RALGPS2 chr1 178725147 178921841 + STRBP chr9 123109500 123268586 - ENO2 chr12 6913745 6923698 + PCYT1B chrX 24558087 24672677 - CTNND1 chr11 57753243 57819546 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC012313.3 chr19 58346854 58362751 - LINC00294 chr11 33076149 33079454 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.