exRNAdisease

Entry Detail

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General Information

Database ID: exR0428834 RNA Name: ACVR1 RNA Type: mRNA Chromosome: chr2 Starnd: - Coordinate: Start Site(bp): 157736444 End Site(bp): 157876330 External Links: ENSG00000115170

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand BCAT1 chr12 24810024 24949101 - BRINP1 chr9 119153458 119369435 - CIT chr12 119685791 119877320 - EIF4B chr12 53006158 53042209 + EWSR1 chr22 29268009 29300525 + IFITM2 chr11 307631 315272 + KPNA4 chr3 160495007 160565571 - MAZ chr16 29806106 29811164 + MRPS5 chr2 95085369 95149434 - MT-CO3 chrMT 9207 9990 + NSL1 chr1 212726153 212791782 - PEF1 chr1 31629866 31644896 - RPS27A chr2 55231903 55235853 + SKAP2 chr7 26667068 26995239 - TCF12 chr15 56918623 57299281 + ZBED6 chr1 203795714 203854999 + ZC3H11A chr1 203795654 203854999 + ZNF468 chr19 52838010 52857649 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-876-5p chr9 28863675 28863696 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.