exRNAdisease

Entry Detail

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General Information

Database ID: exR0428843 RNA Name: AD000671.2 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 35739252 End Site(bp): 35745432 External Links: ENSG00000267120

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ZMAT2 chr5 140698680 140706686 + BSN chr3 49554477 49671549 + PKM chr15 72199029 72231822 - MFSD12 chr19 3538261 3574290 - RPL4 chr15 66498015 66524532 - MAD1L1 chr7 1815793 2233243 - ANKHD1 chr5 140401814 140539856 + DGLUCY chr14 91060333 91225632 + ZNF765 chr19 53389793 53430413 + MTRNR2L12 chr3 96617188 96618236 - CBX3 chr7 26201162 26213607 + TIFA chr4 112274537 112285904 - MEST chr7 130486171 130506465 + CDC37 chr19 10391133 10420121 - CHCHD2 chr7 56101573 56106476 - UCK2 chr1 165827614 165911618 + PSMB8 chr6 32840717 32844679 - POLR1D chr13 27620742 27744237 + MYL6B chr12 56152256 56159647 + INPP5A chr10 132537787 132783480 + SERBP1 chr1 67407810 67430415 - GAPDH chr12 6534512 6538374 + PLIN2 chr9 19108375 19149290 - IGFLR1 chr19 35738801 35742453 - U2AF1L4 chr19 35742464 35745445 - ODC1 chr2 10439968 10448327 - CLIC1 chr6 31730581 31739763 - TRADD chr16 67154185 67159909 - ERCC2 chr19 45349837 45370918 - ACTB chr7 5527148 5563784 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand PCAT7 chr9 94555054 94603990 + SNHG1 chr11 62851984 62855953 - SNHG5 chr6 85650491 85678932 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.