exRNAdisease

Entry Detail

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General Information

Database ID: exR0428844 RNA Name: ADA RNA Type: mRNA Chromosome: chr20 Starnd: - Coordinate: Start Site(bp): 44619522 End Site(bp): 44652233 External Links: ENSG00000196839

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand S100A11 chr1 152032506 152047907 - ELOVL5 chr6 53267398 53349179 - SSR4 chrX 153793516 153798499 + HSP90AB1 chr6 44246166 44253888 + WASHC3 chr12 102012840 102062149 - RAB14 chr9 121178133 121223014 - LAT2 chr7 74199652 74229834 + EEF1A1 chr6 73515750 73523797 - CDKN1A chr6 36676460 36687339 + ZNF703 chr8 37695782 37700019 + NACA chr12 56712427 56731628 - SEC62 chr3 169966635 169998373 + HLA-C chr6 31268749 31272130 - SRSF4 chr1 29147743 29181900 - URB1 chr21 32311018 32393012 - GYPC chr2 126656133 126696667 + PEX5 chr12 7188685 7218574 + AGAP3 chr7 151085831 151144436 + XRCC5 chr2 216107464 216206303 + DVL2 chr17 7225342 7234517 - RPS19 chr19 41860255 41872925 + EVL chr14 99971449 100144236 + MRPL38 chr17 75898643 75905413 - RPL27A chr11 8682788 8714759 + RALY chr20 33993646 34108308 + TUBA1B chr12 49127782 49131397 - NPC2 chr14 74476192 74494177 - CD81 chr11 2376177 2397419 + DRAP1 chr11 65919274 65921563 + SORD chr15 45023181 45077185 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL359924.1 chr1 237862175 237928321 + LINC00996 chr7 150433654 150448140 + SNHG1 chr11 62851984 62855953 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.