exRNAdisease

Entry Detail

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General Information

Database ID: exR0428845 RNA Name: ADA2 RNA Type: mRNA Chromosome: chr22 Starnd: - Coordinate: Start Site(bp): 17178790 End Site(bp): 17258235 External Links: ENSG00000093072

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand SSTR3 chr22 37204237 37212477 - IRF3 chr19 49659569 49665875 - CNN3 chr1 94896949 94927223 - EEF2 chr19 3976056 3985463 - PLRG1 chr4 154535005 154550400 - DDX5 chr17 64498254 64508199 - CSNK2A1 chr20 472498 543835 - ARL6IP1 chr16 18791669 18801572 - HSP90B1 chr12 103930107 103953645 + CTNNA1 chr5 138610967 138935034 + RARRES2 chr7 150338317 150341662 - PAICS chr4 56435741 56464579 + RFWD3 chr16 74621399 74666877 - GRSF1 chr4 70815783 70839897 - TACO1 chr17 63600882 63608365 + C1orf43 chr1 154206696 154220637 - TUBA1A chr12 49184795 49189080 - SMAD2 chr18 47808957 47931146 - TUBB chr6 30720352 30725426 + AC010422.3 chr19 12643831 12648397 - TSPAN6 chrX 100627108 100639991 - FAM136A chr2 70295975 70302090 - CIB2 chr15 78104606 78131535 - RPL13A chr19 49487554 49492308 + RPS4X chrX 72255679 72277248 - CCT7 chr2 73233420 73253021 + CWC27 chr5 64768930 65018750 + MYH10 chr17 8474205 8630761 - CEBPZ chr2 37201612 37231596 - MRPL40 chr22 19431902 19436075 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.