exRNAdisease

Entry Detail

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General Information

Database ID: exR0428855 RNA Name: ADAM23 RNA Type: mRNA Chromosome: chr2 Starnd: + Coordinate: Start Site(bp): 206443532 End Site(bp): 206621127 External Links: ENSG00000114948

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ASCC2 chr22 29788609 29838304 - C10orf82 chr10 116663696 116670264 - C20orf27 chr20 3753508 3768387 - CABP1 chr12 120640552 120667324 + CBL chr11 119206298 119313926 + DDOST chr1 20651767 20661544 - DHRS7B chr17 21123364 21193265 + EIF5A chr17 7306999 7312463 + GMDS chr6 1623806 2245605 - GRINA chr8 143990056 143993415 + HERC2 chr15 28111040 28322172 - HMGB2 chr4 173331376 173334432 - HSP90AB1 chr6 44246166 44253888 + HSP90B1 chr12 103930107 103953645 + IVNS1ABP chr1 185296388 185317273 - MDC1 chr6 30699807 30717447 - NPM1 chr5 171387116 171411137 + PIP4P1 chr14 20457719 20461612 - RPL13 chr16 89560657 89566828 + RPL23 chr17 38847860 38853764 - RRAGA chr9 19049427 19051025 + SLC39A6 chr18 36108531 36129385 - TEKT3 chr17 15303811 15341632 - TMUB2 chr17 44186970 44191929 + USP1 chr1 62436297 62451804 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.