exRNAdisease

Entry Detail

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General Information

Database ID: exR0428860 RNA Name: ADAM8 RNA Type: mRNA Chromosome: chr10 Starnd: - Coordinate: Start Site(bp): 133262420 End Site(bp): 133276868 External Links: ENSG00000151651

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABLIM1 chr10 114431113 114768061 - AC007192.1 chr19 18153158 18178117 + ACLY chr17 41866917 41930542 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - AP1B1 chr22 29327680 29423179 - ASCC2 chr22 29788609 29838304 - AVL9 chr7 32495426 32588726 + BIRC5 chr17 78214186 78225636 + CAND1 chr12 67269358 67319953 + DCAF7 chr17 63550477 63594279 + EBI3 chr19 4229523 4237528 + EEF1B2 chr2 206159585 206162928 + HNRNPK chr9 83968083 83980616 - IFI30 chr19 18173162 18178117 + IGF2 chr11 2129112 2141238 - KIF1C chr17 4997950 5028401 + LRFN4 chr11 66856647 66860475 + MSL3 chrX 11758159 11775772 + OR4K15 chr14 19975444 19976659 + PANK4 chr1 2508537 2526611 - PTGES2 chr9 128120693 128128462 - RABEP2 chr16 28904421 28936526 - RPL35A chr3 197950190 197956610 + RPS9 chr19 54200809 54249003 + SLC7A5 chr16 87830023 87869507 - TFDP1 chr13 113584721 113641473 + TNPO2 chr19 12699194 12724011 - TUBGCP2 chr10 133278630 133312337 - ZFAT chr8 134477788 134713049 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL359924.1 chr1 237862175 237928321 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.