exRNAdisease

Entry Detail

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General Information

Database ID: exR0428861 RNA Name: ADAM9 RNA Type: mRNA Chromosome: chr8 Starnd: + Coordinate: Start Site(bp): 38996869 End Site(bp): 39105261 External Links: ENSG00000168615

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CAPNS1 chr19 36139953 36150353 + ARID3B chr15 74541177 74598131 + TOR1AIP2 chr1 179839967 179877803 - MFSD14C chr9 96887373 97013708 - UHRF1 chr19 4903080 4962154 + PCNP chr3 101574180 101594465 + LDHA chr11 18394560 18408425 + ST8SIA1 chr12 22063773 22437041 - PNMA8A chr19 46466491 46471563 - ORC2 chr2 200908977 200963680 - EEF2 chr19 3976056 3985463 - RPA1 chr17 1829702 1900082 + TCEA1 chr8 53966552 54022456 - TMSB4X chrX 12975110 12977227 + RPL18 chr19 48615328 48619184 - FNIP1 chr5 131641714 131797063 - CANX chr5 179678628 179731641 + POP1 chr8 98117293 98159835 + PLXNA1 chr3 126988594 127037392 + CDK4 chr12 57747727 57756013 - KNTC1 chr12 122527246 122626396 + MT-CO1 chrMT 5904 7445 + RPL4 chr15 66498015 66524532 - TRA2B chr3 185914558 185938103 - EVX2 chr2 176077472 176083913 - NDUFB7 chr19 14566078 14572066 - ACRBP chr12 6638075 6647433 - PRRC1 chr5 127517609 127555089 + HSP90AB1 chr6 44246166 44253888 + LPCAT3 chr12 6976185 7018477 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AP001496.2 chr18 5232876 5238526 - NEAT1 chr11 65422774 65445540 + PIK3CD-AS2 chr1 9672426 9687555 - SLFNL1-AS1 chr1 41014590 41043890 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.