exRNAdisease

Entry Detail

---



General Information

Database ID: exR0428863 RNA Name: ADAMTS1 RNA Type: mRNA Chromosome: chr21 Starnd: - Coordinate: Start Site(bp): 26835755 End Site(bp): 26845409 External Links: ENSG00000154734

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RBM39 chr20 35701347 35742312 - KATNBL1 chr15 34140674 34210096 - SCRN1 chr7 29920104 29990289 - NPIPA8 chr16 18317942 18336736 - HECTD4 chr12 112160188 112382439 - MRPL38 chr17 75898643 75905413 - IDH2 chr15 90083045 90102504 - SEC31A chr4 82818509 82901166 - HNRNPCL2 chr1 13115488 13116854 - TMEM259 chr19 1009648 1021179 - RECQL5 chr17 75626845 75667189 - TAX1BP3 chr17 3662895 3668679 - MARK4 chr19 45079288 45305284 + GPI chr19 34359480 34402413 + HCFC1 chrX 153947557 153971818 - FAM13B chr5 137937960 138051961 - TAOK2 chr16 29973868 29992261 + TM9SF3 chr10 96518110 96587452 - MINDY4 chr7 30771417 30892387 + KIF13A chr6 17759183 17987635 - SOX9 chr17 72121020 72126416 + ATIC chr2 215311956 215349773 + RRM1 chr11 4094707 4138932 + TMEM179B chr11 62787402 62790400 + UBE2W chr8 73780097 73878910 - GMPPB chr3 49716844 49723951 - EMC9 chr14 24138959 24141591 - AC087289.3 chr17 75898645 75930129 - SON chr21 33543038 33577481 + PIP4K2A chr10 22534854 22714578 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC040160.2 chr16 67261108 67263784 + GATA2-AS1 chr3 128489212 128502970 + RMRP chr9 35657751 35658018 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.