exRNAdisease

Entry Detail

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General Information

Database ID: exR0428866 RNA Name: ADAMTS13 RNA Type: mRNA Chromosome: chr9 Starnd: + Coordinate: Start Site(bp): 133414358 End Site(bp): 133459402 External Links: ENSG00000160323

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ATXN10 chr22 45671798 45845307 + BCR chr22 23179704 23318037 + CCDC124 chr19 17933015 17943991 + DDX24 chr14 94048287 94081212 - EME2 chr16 1772810 1781708 + ESYT1 chr12 56118250 56144671 + GCN1 chr12 120127202 120194715 - GDI2 chr10 5765223 5842132 - GNS chr12 64713445 64759431 - LUC7L chr16 188969 229463 - MAPK9 chr5 180233143 180292099 - MARCKSL1 chr1 32333839 32336233 - NDUFV1 chr11 67605653 67612554 + PDXK chr21 43719094 43762307 + PLEKHJ1 chr19 2230084 2237704 - PPP2R1A chr19 52190048 52229518 + PTOV1 chr19 49850735 49860744 + PTPN11 chr12 112418351 112509913 + SPG11 chr15 44562696 44663678 - SPG7 chr16 89490719 89557768 + SUV39H1 chrX 48695554 48709012 + WDR34 chr9 128633661 128656787 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC121761.1 chr12 75483454 75489820 - AC124068.2 chr15 89335053 89336161 + Z95331.1 chr22 45657019 45680130 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.