exRNAdisease

Entry Detail

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General Information

Database ID: exR0428869 RNA Name: ADAMTS17 RNA Type: mRNA Chromosome: chr15 Starnd: - Coordinate: Start Site(bp): 99971437 End Site(bp): 100342005 External Links: ENSG00000140470

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC022384.1 chr3 10249372 10285796 + ATXN7L3 chr17 44191805 44200113 - BRD4 chr19 15235519 15332545 - E2F2 chr1 23506438 23531233 - EIF4G3 chr1 20806292 21176888 - ERCC1 chr19 45407333 45478828 - FUBP3 chr9 130578965 130638352 + LAMA3 chr18 23689443 23956222 + LAMA5 chr20 62307955 62367312 - MAP1B chr5 72107234 72209565 + NCOR1 chr17 16029157 16218185 - PKN1 chr19 14433053 14471867 + PTPRU chr1 29236516 29326813 + SELENOS chr15 101270817 101277500 - TATDN2 chr3 10248023 10281218 + TICRR chr15 89575469 89631056 + TMEM151B chr6 44270450 44307506 + miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.