exRNAdisease

Entry Detail

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General Information

Database ID: exR0428871 RNA Name: ADAMTS19 RNA Type: mRNA Chromosome: chr5 Starnd: + Coordinate: Start Site(bp): 129460281 End Site(bp): 129738683 External Links: ENSG00000145808

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RIT1 chr1 155897808 155911404 - NSFL1C chr20 1442162 1473842 - SCFD2 chr4 52872982 53366066 - RPL23A chr17 28719985 28724359 + TPT1 chr13 45333471 45341370 - GRK5 chr10 119207571 119459745 + GPR137C chr14 52552836 52637713 + SMPD2 chr6 109440724 109443919 + FAM124A chr13 51222334 51284241 + TSPAN6 chrX 100627108 100639991 - ZNF614 chr19 52012765 52030240 - EIF2D chr1 206571292 206612465 - GATA5 chr20 62463497 62475995 - CCZ1 chr7 5898725 5926550 + BZW1 chr2 200810594 200827338 + RPL3 chr22 39312882 39320389 - SYPL1 chr7 106090503 106112576 - BTAF1 chr10 91923770 92030325 + XPO6 chr16 28097979 28211920 - STX8 chr17 9250471 9576591 - HNRNPH3 chr10 68331174 68343191 + KHDRBS1 chr1 32013868 32060850 + RARB chr3 25174332 25597932 + FBXL19 chr16 30923055 30948783 + TPR chr1 186311652 186375693 - ATXN10 chr22 45671798 45845307 + SLC38A1 chr12 46183063 46270017 - NRAS chr1 114704469 114716771 - FLNA chrX 154348524 154374638 - DDOST chr1 20651767 20661544 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.