exRNAdisease

Entry Detail

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General Information

Database ID: exR0428885 RNA Name: ADAR RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 154582057 End Site(bp): 154628013 External Links: ENSG00000160710

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand KIAA0040 chr1 175156986 175192999 - HLA-B chr6 31269491 31357188 - AC007192.1 chr19 18153158 18178117 + TMSB4X chrX 12975110 12977227 + NTAN1 chr16 15037854 15056079 - RPS14 chr5 150442635 150449739 - CLCN6 chr1 11806096 11848079 + KAT7 chr17 49788681 49835026 + SIK3 chr11 116843402 117098437 - TMEM147 chr19 35545600 35547526 + MAN2C1 chr15 75355207 75368612 - LPXN chr11 58526871 58578220 - AURKB chr17 8204733 8210600 - SSR1 chr6 7268306 7347446 - DHCR24 chr1 54849627 54887195 - RPS8 chr1 44775251 44778779 + ATP5PF chr21 25716503 25735673 - RPL27A chr11 8682788 8714759 + TMEM69 chr1 45688181 45694436 + TMED10 chr14 75131469 75176612 - PACSIN2 chr22 42835412 43015149 - UFM1 chr13 38349849 38363619 + OAS3 chr12 112938444 112973251 + SRC chr20 37344685 37406050 + ERP29 chr12 112013348 112023449 + HLA-DPA1 chr6 33064569 33080775 - ZFR chr5 32354350 32444740 - CAPRIN1 chr11 34051731 34102610 + PKM chr15 72199029 72231822 - STARD7 chr2 96184859 96208825 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-130b-3p chr22 21653354 21653375 + hsa-miR-373-3p chr19 53788748 53788770 + hsa-miR-520e-3p chr19 53675764 53675784 + hsa-miR-519c-3p chr19 53686522 53686543 + hsa-miR-519b-3p chr19 53695263 53695284 + hsa-miR-520b-3p chr19 53701267 53701287 + hsa-miR-520c-3p chr19 53707506 53707527 + hsa-miR-4426 chr1 192716333 192716349 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC009163.4 chr16 75458252 75460017 - AC135178.2 chr17 8318088 8318712 - AL139819.1 chr10 100335563 100346390 - LHFPL3-AS2 chr7 104894628 104926645 - LINC01273 chr20 50171809 50176676 + RMST chr12 97430884 97598415 + THAP7-AS1 chr22 21001886 21010342 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.