exRNAdisease

Entry Detail

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General Information

Database ID: exR0428886 RNA Name: ADARB1 RNA Type: mRNA Chromosome: chr21 Starnd: + Coordinate: Start Site(bp): 45073853 End Site(bp): 45226560 External Links: ENSG00000197381

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand UBB chr17 16380798 16382745 + LBHD1 chr11 62662817 62672255 - TNPO2 chr19 12699194 12724011 - TXNRD2 chr22 19875517 19941820 - TMEM131 chr2 97756333 97995948 - EXOSC10 chr1 11066618 11099869 - IFT140 chr16 1510427 1612072 - ZFR chr5 32354350 32444740 - RPL37A chr2 216498825 216579180 + RAC2 chr22 37225270 37244448 - IGF1R chr15 98648539 98964530 + CAD chr2 27217369 27243943 + WDR45B chr17 82614562 82648553 - HMGA1 chr6 34236873 34246231 + SLC9A3R1 chr17 74748628 74769353 + PSMA4 chr15 78540405 78552417 + MYCN chr2 15940550 15947007 + MAPK12 chr22 50245450 50261716 - RPS14 chr5 150442635 150449739 - PIP4K2C chr12 57591174 57603418 + PIP5K1A chr1 151197949 151249536 + SYNJ2BP-COX16 chr14 70326064 70417074 - AC120114.4 chr16 29817239 29830627 + RANBP1 chr22 20115938 20127355 + COASY chr17 42561467 42566277 + HNRNPU chr1 244840638 244864560 - GFOD2 chr16 67674531 67719339 - SPON1 chr11 13962723 14268133 + COX16 chr14 70325081 70416984 - AUTS2 chr7 69598296 70793506 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-17-5p chr13 91350618 91350640 + hsa-miR-20a-5p chr13 91351072 91351094 + hsa-miR-93-5p chr7 100093815 100093837 - hsa-miR-106a-5p chrX 134170244 134170266 - hsa-miR-301a-3p chr17 59151149 59151171 - hsa-miR-20b-5p chrX 134169850 134169872 - hsa-miR-512-3p chr19 53666729 53666750 + hsa-miR-454-3p chr17 59137787 59137809 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand SNHG7 chr9 136721366 136728184 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.