exRNAdisease

Entry Detail

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General Information

Database ID: exR0428888 RNA Name: ADAT1 RNA Type: mRNA Chromosome: chr16 Starnd: - Coordinate: Start Site(bp): 75596981 End Site(bp): 75623300 External Links: ENSG00000065457

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand BFAR chr16 14632931 14669236 + CD22 chr19 35319261 35347361 + CD48 chr1 160678746 160711831 - CFDP1 chr16 75293698 75433503 - CREB3L2 chr7 137874979 138002086 - FUT11 chr10 73772276 73780251 + HNRNPM chr19 8444767 8489114 + IGF2 chr11 2129112 2141238 - KCNC3 chr19 50311937 50333515 - KMT2B chr19 35717973 35738878 + MAEA chr4 1289887 1340147 + METRN chr16 715118 719655 + NME1-NME2 chr17 51153590 51171744 + NME2 chr17 51165435 51171747 + NT5DC2 chr3 52524385 52535054 - PAK1 chr11 77321707 77474635 - RPP14 chr3 58306247 58324695 + STT3A chr11 125591712 125625215 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC025287.1 chr16 75541399 75608445 - KCNQ1OT1 chr11 2608328 2699994 - MALAT1 chr11 65497688 65506516 + ZNF710-AS1 chr15 90074512 90082207 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.