exRNAdisease

Entry Detail

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General Information

Database ID: exR0428889 RNA Name: ADAT2 RNA Type: mRNA Chromosome: chr6 Starnd: - Coordinate: Start Site(bp): 143422832 End Site(bp): 143450695 External Links: ENSG00000189007

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC011511.4 chr19 10315471 10320678 - AC118549.1 chr1 77562416 77683419 - AP002990.1 chr11 62559603 62591531 - ATP5F1B chr12 56638175 56645984 - B4GALT6 chr18 31622247 31685836 - DDI2 chr1 15617458 15669044 + DUSP1 chr5 172768096 172771195 - EEF1A1 chr6 73515750 73523797 - EEF1G chr11 62559596 62574086 - FBXO31 chr16 87326987 87392142 - FBXO41 chr2 73254682 73284431 - FNDC3B chr3 172039578 172401669 + GLO1 chr6 38675925 38703145 - KNTC1 chr12 122527246 122626396 + LEPROT chr1 65420587 65436007 + PSME1 chr14 24136163 24138967 + RAVER1 chr19 10316212 10333638 - RPS6KB2 chr11 67428460 67435401 + RSC1A1 chr1 15659869 15661722 + SRSF10 chr1 23964347 23980927 - YWHAQ chr2 9583967 9630997 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-18a-5p chr13 91350756 91350778 + hsa-miR-18b-5p chrX 134170084 134170106 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.