exRNAdisease

Entry Detail

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General Information

Database ID: exR0428890 RNA Name: ADAT3 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 1905399 End Site(bp): 1913447 External Links: ENSG00000213638

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand STRN3 chr14 30893799 31026401 - DBN1 chr5 177456608 177474401 - NUDT19 chr19 32691961 32713796 + STARD9 chr15 42575606 42720998 + KRT18 chr12 52948871 52952906 + JUND chr19 18279694 18281622 - MLLT6 chr17 38705273 38729795 + TMEM256-PLSCR3 chr17 7389734 7404097 - LARP1 chr5 154712843 154817605 + SYMPK chr19 45815410 45863194 - SLC9A3R1 chr17 74748628 74769353 + EXOSC2 chr9 130693721 130704894 + TMEM132A chr11 60924463 60937159 + HNRNPAB chr5 178204533 178211163 + DHX38 chr16 72093613 72112912 + HNRNPK chr9 83968083 83980616 - PLSCR3 chr17 7389727 7394842 - RPS28 chr19 8321158 8323340 + C5AR1 chr19 47290023 47322066 + DZIP1 chr13 95578202 95644703 - CIC chr19 42268537 42295797 + ZNF721 chr4 425815 499156 - SRSF4 chr1 29147743 29181900 - SIRPA chr20 1894167 1940592 + SCAMP4 chr19 1905372 1926013 + ARAP1 chr11 72685069 72793599 - RAN chr12 130872037 130877678 + HTT chr4 3041422 3243960 + PKMYT1 chr16 2968024 2980479 - CYB5R3 chr22 42617840 42649392 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand MIRLET7BHG chr22 46053869 46113928 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.