exRNAdisease

Entry Detail

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General Information

Database ID: exR0428892 RNA Name: ADCK2 RNA Type: mRNA Chromosome: chr7 Starnd: + Coordinate: Start Site(bp): 140672945 End Site(bp): 140696261 External Links: ENSG00000133597

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand TXNIP chr1 145992435 145996579 - RPL13A chr19 49487554 49492308 + RPS25 chr11 119015712 119018691 - RBM47 chr4 40423267 40630875 - INPPL1 chr11 72223701 72239147 + CCAR2 chr8 22604632 22621514 + PLCXD1 chrX 276322 303356 + ITGB2 chr21 44885953 44931989 - NDUFV1 chr11 67605653 67612554 + POGK chr1 166839447 166856344 + MTRNR2L12 chr3 96617188 96618236 - POC1A chr3 52075226 52154690 - HBS1L chr6 134960378 135103056 - RPL27A chr11 8682788 8714759 + RPL35 chr9 124857880 124861981 - NYNRIN chr14 24399003 24419283 + PTMA chr2 231706895 231713541 + TUBA1C chr12 49188736 49274603 + SOX11 chr2 5692384 5701385 + LARP4B chr10 806914 931705 - NDUFB2 chr7 140690777 140722790 + HNRNPA2B1 chr7 26173057 26201529 - RBMX chrX 136848004 136880764 - RPS3 chr11 75399515 75422280 + SPEN chr1 15836095 15940456 + COX10 chr17 14069490 14231736 + ABCA2 chr9 137007234 137028922 - CSE1L chr20 49046246 49096960 + DDHD2 chr8 38225218 38275558 + LSM12 chr17 44034328 44067619 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.