exRNAdisease

Entry Detail

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General Information

Database ID: exR0428894 RNA Name: ADCY1 RNA Type: mRNA Chromosome: chr7 Starnd: + Coordinate: Start Site(bp): 45574140 End Site(bp): 45723116 External Links: ENSG00000164742

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand HLA-A chr6 29941260 29945884 + RBMXL1 chr1 88979456 88992960 - CTTN chr11 70398404 70436584 + SCYL1 chr11 65525077 65538704 + FP565260.1 chr21 5130871 5154658 - ICE1 chr5 5420664 5490220 + GNAS chr20 58839718 58911192 + NFATC2IP chr16 28950807 28967097 + SV2A chr1 149903318 149917844 - GLRX3 chr10 130136391 130184521 + LAMA5 chr20 62307955 62367312 - MFSD1 chr3 158732198 158829719 + TMEM185A chrX 149596556 149631912 - UBXN4 chr2 135741734 135785056 + C6orf62 chr6 24704861 24719998 - SZRD1 chr1 16352575 16398145 + PWP2 chr21 44107373 44131181 + MBP chr18 76978827 77133683 - ATP5MC2 chr12 53632726 53677408 - KLF2 chr19 16324817 16327874 + GAPDH chr12 6534512 6538374 + KAT2A chr17 42113111 42121367 - HUWE1 chrX 53532096 53686728 - RAB5A chr3 19947097 19985175 + PHB2 chr12 6965327 6970753 - MARCKS chr6 113857345 113863475 + SUMO3 chr21 44805617 44818779 - NCOA6 chr20 34689097 34825651 - FBRSL1 chr12 132489551 132585188 + LAMB1 chr7 107923799 108003187 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand LINC00665 chr19 36313067 36331770 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.