exRNAdisease

Entry Detail

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General Information

Database ID: exR0428896 RNA Name: ADCY2 RNA Type: mRNA Chromosome: chr5 Starnd: + Coordinate: Start Site(bp): 7396138 End Site(bp): 7830081 External Links: ENSG00000078295

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RTN4 chr2 54972187 55112621 - RBBP5 chr1 205086142 205122015 - DMAC1 chr9 7796500 7888380 - HIPK2 chr7 139561570 139777998 - GDI2 chr10 5765223 5842132 - TUFT1 chr1 151540305 151583583 + ACTR1B chr2 97655939 97664044 - NAP1L1 chr12 76036585 76084958 - KREMEN2 chr16 2964216 2968383 + RASSF8 chr12 25959029 26079892 + CTSV chr9 97029677 97039643 - SH3BP4 chr2 234952017 235055714 + ZSCAN10 chr16 3088890 3099295 - PHB2 chr12 6965327 6970753 - ADCY5 chr3 123282296 123449758 - SDCBP chr8 58552924 58582859 + CRABP1 chr15 78340353 78348225 + HSP90AB1 chr6 44246166 44253888 + LIN28A chr1 26410817 26429728 + DSG2 chr18 31498177 31549008 + AURKAIP1 chr1 1373730 1375495 - OGG1 chr3 9749944 9788219 + APEH chr3 49674014 49683971 + GNAS chr20 58839718 58911192 + PSMD10 chrX 108084207 108091549 - SF3B1 chr2 197388515 197435091 - PANK1 chr10 89579497 89645572 - MYL6 chr12 56158161 56163496 + ANAPC15 chr11 72106378 72112780 - YWHAE chr17 1344275 1400222 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.