exRNAdisease

Entry Detail

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General Information

Database ID: exR0428899 RNA Name: ADCY5 RNA Type: mRNA Chromosome: chr3 Starnd: - Coordinate: Start Site(bp): 123282296 End Site(bp): 123449758 External Links: ENSG00000173175

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand RPS6 chr9 19375715 19380236 - PELP1 chr17 4669774 4704337 - PHF3 chr6 63635820 63779336 + AC010422.3 chr19 12643831 12648397 - GCN1 chr12 120127202 120194715 - PINK1 chr1 20633458 20651511 + TUBB2A chr6 3153666 3157544 - HSP90AA1 chr14 102080738 102139699 - GPRC5C chr17 74424851 74451653 + RHOB chr2 20447074 20449440 + LRFN3 chr19 35935358 35946624 + AC008878.1 chr19 7507052 7519622 + DGKZ chr11 46332905 46380554 + AL136295.5 chr14 24147548 24166452 + MRPL36 chr5 1798385 1801366 - RPL3 chr22 39312882 39320389 - ICE2 chr15 60419609 60479160 - FAM83D chr20 38926312 38953106 + STK39 chr2 167954020 168247595 - THOC5 chr22 29505879 29555216 - ACOT7 chr1 6264269 6394391 - JPT2 chr16 1678256 1702280 + ZNF358 chr19 7515292 7521025 + TUBA1B chr12 49127782 49131397 - SKAP2 chr7 26667068 26995239 - RCC2 chr1 17406760 17439677 - ZNF253 chr19 19865882 19894674 + SLC37A3 chr7 140293693 140404433 - STK10 chr5 172042079 172188224 - RPL8 chr8 144789765 144792587 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC092902.2 chr3 125774714 125797953 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.