exRNAdisease

Entry Detail

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General Information

Database ID: exR0428900 RNA Name: ADCY6 RNA Type: mRNA Chromosome: chr12 Starnd: - Coordinate: Start Site(bp): 48766194 End Site(bp): 48789037 External Links: ENSG00000174233

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand MACF1 chr1 39081316 39487177 + SLC25A29 chr14 100291116 100306547 - HSP90AB1 chr6 44246166 44253888 + CALM1 chr14 90396502 90408268 + PRRT4 chr7 128350325 128361685 - LCMT1 chr16 25111731 25178231 + FLNA chrX 154348524 154374638 - TPM4 chr19 16067021 16103002 + FADS2 chr11 61792980 61867354 + MYBBP1A chr17 4538897 4555631 - UBB chr17 16380798 16382745 + RNF167 chr17 4940008 4945222 + PUS1 chr12 131929200 131945896 + LRCH4 chr7 100574011 100586129 - SELENOP chr5 42799880 42887392 - ARID1A chr1 26693236 26782104 + PEX19 chr1 160276812 160286348 - IGF2 chr11 2129112 2141238 - FNDC3B chr3 172039578 172401669 + HUWE1 chrX 53532096 53686728 - PDCD7 chr15 65117379 65133808 - LENG8 chr19 54448887 54462037 + SYNM chr15 99098217 99135593 + EME2 chr16 1772810 1781708 + FNTB chr14 64986895 65062652 + SMARCD1 chr12 50085200 50100707 + SNTB2 chr16 69187129 69309052 + ZNF628 chr19 55476617 55484487 + SNRPF chr12 95858928 95903828 + TAZ chrX 154411524 154421726 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC069281.2 chr7 100572232 100578700 - AC138761.1 chr17 22266395 22288301 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.