exRNAdisease

Entry Detail

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General Information

Database ID: exR0428901 RNA Name: ADCY7 RNA Type: mRNA Chromosome: chr16 Starnd: + Coordinate: Start Site(bp): 50246137 End Site(bp): 50318135 External Links: ENSG00000121281

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACTG1 chr17 81509971 81523847 - ADCY4 chr14 24318349 24335093 - CNTROB chr17 7932101 7949920 + FTL chr19 48965309 48966879 + GLUD1 chr10 87050202 87094843 - GSTP1 chr11 67583742 67586656 + HSPE1 chr2 197500140 197503449 + MRPS6 chr21 34073224 34143034 + PNMA8A chr19 46466491 46471563 - RPL4 chr15 66498015 66524532 - RPL7A chr9 133348218 133351426 + SBNO2 chr19 1107637 1174268 - SLC5A3 chr21 34073578 34106260 + SRGN chr10 69088103 69104805 + SYNGR2 chr17 78168558 78173527 + TMEM189-UBE2V1 chr20 50081124 50153637 - TPT1 chr13 45333471 45341370 - TTC38 chr22 46267961 46294008 + UBE2V1 chr20 50081124 50115959 - ZFP36L1 chr14 68787660 68796253 - ZHX3 chr20 41178448 41317672 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AP000317.2 chr21 34073592 34360033 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.