exRNAdisease

Entry Detail

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General Information

Database ID: exR0428907 RNA Name: ADD2 RNA Type: mRNA Chromosome: chr2 Starnd: - Coordinate: Start Site(bp): 70607618 End Site(bp): 70768225 External Links: ENSG00000075340

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand COL21A1 chr6 56056590 56394094 - PRKD3 chr2 37250502 37324808 - SMIM20 chr4 25861830 25929874 + CNN3 chr1 94896949 94927223 - SHISA5 chr3 48467798 48504826 - PRUNE1 chr1 151008420 151035713 + FUBP3 chr9 130578965 130638352 + YWHAB chr20 44885702 44908532 + USP40 chr2 233475520 233566782 - DYNC1H1 chr14 101964573 102056443 + YIPF4 chr2 32277904 32316594 + RPS6 chr9 19375715 19380236 - C12orf75 chr12 105235290 105396097 + AC138894.1 chr16 28456371 28492098 - PPID chr4 158709127 158723396 - P4HB chr17 81843161 81860624 - CMSS1 chr3 99817837 100181732 + HSP90AB1 chr6 44246166 44253888 + TREX2 chrX 153444720 153470587 - AAK1 chr2 69457997 69674349 - RPL11 chr1 23691742 23696835 + MAP3K3 chr17 63622415 63696303 + ANKRD13C chr1 70258999 70354734 - ATP5F1D chr19 1241746 1244825 + GDF11 chr12 55743122 55757264 + ZMIZ2 chr7 44748581 44769881 + SRSF9 chr12 120461672 120469748 - SHMT1 chr17 18327860 18363563 - RPL4 chr15 66498015 66524532 - GTPBP1 chr22 38705742 38738299 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC245014.3 chr1 145281116 145281462 + AL356489.2 chr9 33697459 33700986 + FOXD3-AS1 chr1 63320884 63324441 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.