exRNAdisease

Entry Detail

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General Information

Database ID: exR0428908 RNA Name: ADD3 RNA Type: mRNA Chromosome: chr10 Starnd: + Coordinate: Start Site(bp): 109996368 End Site(bp): 110135565 External Links: ENSG00000148700

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ZNF90 chr19 20077994 20127076 + SLC2A3 chr12 7919230 7936187 - C16orf72 chr16 9091644 9121635 + SMARCB1 chr22 23786931 23838008 + MAGI1 chr3 65353525 66038834 - STK26 chrX 132023302 132075943 + GGH chr8 63015079 63038806 - AASS chr7 122073549 122144255 - AC011462.1 chr19 41350853 41425001 + COPS3 chr17 17246616 17281273 - HDGF chr1 156742109 156766925 - ATP6V1G1 chr9 114587769 114598879 + TIMELESS chr12 56416363 56449426 - CNTNAP2 chr7 146116002 148420998 + CNTN2 chr1 205042937 205078289 + TBCD chr17 82752065 82945914 + TM9SF4 chr20 32109714 32167258 + EXOSC8 chr13 36998816 37009614 + KHNYN chr14 24429286 24441843 + CLTA chr9 36190856 36304781 + MEST chr7 130486171 130506465 + MT-CO1 chrMT 5904 7445 + SELENOF chr1 86862445 86914424 - TOX4 chr14 21476597 21499175 + TMED5 chr1 93149742 93180516 - HILPDA chr7 128455849 128458418 + BCAS3 chr17 60677453 61392838 + RBMX chrX 136848004 136880764 - MRPS23 chr17 57834781 57850056 - TPT1 chr13 45333471 45341370 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002470.2 chr22 20979462 20998121 + AC020928.1 chr19 36773112 36777078 + MALAT1 chr11 65497688 65506516 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.