exRNAdisease

Entry Detail

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General Information

Database ID: exR0428912 RNA Name: ADGRA3 RNA Type: mRNA Chromosome: chr4 Starnd: - Coordinate: Start Site(bp): 22345071 End Site(bp): 22516066 External Links: ENSG00000152990

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand SPTLC3 chr20 13008972 13169103 + EP400 chr12 131949942 132080460 + PMM1 chr22 41576900 41589871 - EHD4 chr15 41895933 41972557 - DBNDD1 chr16 90004871 90020128 - FAM49B chr8 129839593 130017129 - CANX chr5 179678628 179731641 + CLIC4 chr1 24745382 24844321 + PTMA chr2 231706895 231713541 + SLC35A4 chr5 140564828 140569100 + USP53 chr4 119212587 119295517 + SLC2A1 chr1 42925375 42958868 - FTL chr19 48965309 48966879 + TMEM184B chr22 38219291 38273010 - SLC25A11 chr17 4937130 4940053 - CXXC4 chr4 104468308 104494901 - YLPM1 chr14 74763316 74859435 + FNTA chr8 43034194 43085788 + ACACA chr17 37084992 37406836 - ZBTB6 chr9 122908056 122913323 - ATIC chr2 215311956 215349773 + MTCH1 chr6 36968141 36986298 - EPN1 chr19 55675226 55709858 + EIF3A chr10 119033670 119080823 - YWHAZ chr8 100916523 100953388 - STOM chr9 121338987 121370304 - DHCR24 chr1 54849627 54887195 - RPLP1 chr15 69452814 69456205 + MT-ATP8 chrMT 8366 8572 + ZMYM4 chr1 35268709 35422058 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC009022.1 chr16 69976297 70065948 - AC079949.1 chr12 127142029 127146532 - HLA-F-AS1 chr6 29726601 29749049 - LINC00458 chr13 54115783 54142319 - MUC20-OT1 chr3 195658062 195739964 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.