exRNAdisease

Entry Detail

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General Information

Database ID: exR0428914 RNA Name: ADGRB2 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 31727117 End Site(bp): 31764893 External Links: ENSG00000121753

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ANAPC2 chr9 137174784 137188560 - ARGLU1 chr13 106541673 106568137 - ARIH1 chr15 72474330 72602987 + ATP2B1 chr12 89588049 89709300 - CBLB chr3 105655461 105869552 - CMTR1 chr6 37433219 37482827 + CSNK1E chr22 38290691 38318084 - DCAF7 chr17 63550477 63594279 + DZIP1 chr13 95578202 95644703 - EEF2 chr19 3976056 3985463 - GANAB chr11 62624826 62646726 - INPP4A chr2 98444854 98594390 + MCRIP2 chr16 636817 648474 + NAV1 chr1 201622885 201826969 + PGK1 chrX 77910739 78129295 + PGM1 chr1 63593411 63660245 + PUS3 chr11 125893485 125903221 - RNF40 chr16 30761745 30776307 + SEC11C chr18 59139866 59158832 + TICRR chr15 89575469 89631056 + TYSND1 chr10 70137981 70146700 - VKORC1L1 chr7 65873074 65959563 + VPS35 chr16 46656132 46689518 - WDR1 chr4 10074339 10116949 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.