exRNAdisease

Entry Detail

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General Information

Database ID: exR0428920 RNA Name: ADGRE5 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 14380501 End Site(bp): 14408725 External Links: ENSG00000123146

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand PHLPP1 chr18 62715541 62980433 + FLNA chrX 154348524 154374638 - AL136454.1 chr1 192716132 192716653 + RPL36A chrX 101390824 101396154 + MCRS1 chr12 49556544 49568145 - SRCAP chr16 30698209 30741409 + KRI1 chr19 10553085 10566031 - NUP62 chr19 49906825 49929763 - SEPHS2 chr16 30443631 30445874 - TMSB4X chrX 12975110 12977227 + EEF1D chr8 143579697 143599541 - NLN chr5 65722205 65871725 + EDARADD chr1 236348257 236502915 + ADGRE2 chr19 14732392 14778560 - PRKCB chr16 23835983 24220611 + TMUB2 chr17 44186970 44191929 + NCAPH chr2 96335766 96377091 + RPL27A chr11 8682788 8714759 + KXD1 chr19 18557762 18569387 + RPS14 chr5 150442635 150449739 - RPL36A-HNRNPH2 chrX 101391011 101412297 + MKNK2 chr19 2037465 2051244 - EOGT chr3 68975217 69013684 - MTRNR2L12 chr3 96617188 96618236 - SYN2 chr3 12004388 12192032 + TNPO2 chr19 12699194 12724011 - GJA3 chr13 20138255 20161052 - TMEM30A chr6 75252924 75284948 - UBIAD1 chr1 11273206 11296049 + RNF167 chr17 4940008 4945222 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-588 chr6 126484646 126484666 + circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.