exRNAdisease

Entry Detail

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General Information

Database ID: exR0428926 RNA Name: ADGRG2 RNA Type: mRNA Chromosome: chrX Starnd: - Coordinate: Start Site(bp): 18989307 End Site(bp): 19122637 External Links: ENSG00000173698

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand PFKL chr21 44300051 44327376 + CTSH chr15 78921058 78949574 - FASN chr17 82078338 82098294 - ANKHD1 chr5 140401814 140539856 + HMGA1 chr6 34236873 34246231 + PPP1R9B chr17 50133737 50150677 - FLAD1 chr1 154983338 154993111 + CBX3 chr7 26201162 26213607 + ABCA3 chr16 2275881 2340746 - SH3D19 chr4 151102751 151325632 - KPNA1 chr3 122421902 122514945 - HLA-B chr6 31269491 31357188 - NPIPB3 chr16 21402237 21448567 - ANKHD1-EIF4EBP3 chr5 140401908 140549569 + AC120114.4 chr16 29817239 29830627 + XPO6 chr16 28097979 28211920 - ZNF623 chr8 143636013 143656418 + PCGF2 chr17 38733898 38749817 - BDP1 chr5 71455651 71567820 + LRP3 chr19 33177603 33208864 + RTL6 chr22 44492583 44498233 - HMG20B chr19 3572777 3579088 + E2F2 chr1 23506438 23531233 - ARID1B chr6 156776020 157210779 + TNPO2 chr19 12699194 12724011 - WRNIP1 chr6 2765393 2786952 + EIF4H chr7 74174245 74197101 + LRWD1 chr7 102464956 102473168 + PIM2 chrX 48913182 48919024 - TMEM184B chr22 38219291 38273010 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008738.7 chr19 33207129 33207639 + AD000090.1 chr19 35557956 35581954 + CYTOR chr2 87454781 87636740 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.