exRNAdisease

Entry Detail

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General Information

Database ID: exR0428930 RNA Name: ADGRG6 RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 142301854 End Site(bp): 142446266 External Links: ENSG00000112414

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand TAF15 chr17 35713791 35864615 + JPH4 chr14 23568035 23578790 - RPS16 chr19 39433137 39435949 - NPM1 chr5 171387116 171411137 + TRAK1 chr3 42013802 42225890 + PFDN1 chr5 140245035 140303113 - PHB chr17 49404049 49414905 - TPM1 chr15 63042632 63071915 + RPL7A chr9 133348218 133351426 + CYP26A1 chr10 93073475 93077885 + RPL19 chr17 39200283 39204732 + IGF2 chr11 2129112 2141238 - SREBF2 chr22 41833079 41907307 + GLI2 chr2 120735623 120992653 + MTRNR2L8 chr11 10507894 10509186 - TUBA1B chr12 49127782 49131397 - LRCH3 chr3 197791226 197888436 + SPTLC1 chr9 92000087 92115413 - ZNF585B chr19 37181579 37218153 - GNB1 chr1 1785285 1891117 - EPN1 chr19 55675226 55709858 + TXNRD1 chr12 104215779 104350307 + FAM171A1 chr10 15211643 15371289 - DDX3X chrX 41333284 41364472 + SUCLG2 chr3 67360460 67654614 - CCT6A chr7 56051685 56063989 + DDX39B chr6 31530219 31542448 - CENPJ chr13 24882279 24922889 - ANG chr14 20684177 20698971 + TTC21B chr2 165857475 165953816 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-23a-3p chr19 13836595 13836615 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand ARHGAP27P1-BPTFP1-KPNA2P3 chr17 64749663 64781707 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.