exRNAdisease

Entry Detail

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General Information

Database ID: exR0428933 RNA Name: ADGRL2 RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 81306160 End Site(bp): 81992436 External Links: ENSG00000117114

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand PRPF4B chr6 4021267 4064983 + RPS18 chr6 33272075 33276511 + RBM39 chr20 35701347 35742312 - CBX3 chr7 26201162 26213607 + NSD1 chr5 177133025 177300215 + FUS chr16 31180110 31194871 + ATP5F1B chr12 56638175 56645984 - FAM199X chrX 104166453 104195902 + PSMA6 chr14 35278633 35317493 + LMO4 chr1 87328880 87348923 + RPL27A chr11 8682788 8714759 + KIF5B chr10 32009015 32056425 - RBM14-RBM4 chr11 66616626 66646469 + FOXO3 chr6 108559835 108684774 + RBM4 chr11 66638617 66668374 + MRFAP1 chr4 6640091 6642745 + CPEB3 chr10 92046692 92291078 - MED18 chr1 28329002 28335965 + PCID2 chr13 113177536 113208715 - ASNSD1 chr2 189661385 189670831 + TTC7A chr2 46916157 47076137 + YBX1 chr1 42682418 42703805 + POM121C chr7 75416786 75486299 - TXNL4A chr18 79970813 80033949 - MARCKS chr6 113857345 113863475 + EDARADD chr1 236348257 236502915 + PUM1 chr1 30931506 31065991 - UBQLN1 chr9 83659968 83707958 - ANAPC2 chr9 137174784 137188560 - GNAS chr20 58839718 58911192 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AD000090.1 chr19 35557956 35581954 + AC022034.1 chr8 53493523 53524336 - JPX chrX 73944182 74070408 + NEAT1 chr11 65422774 65445540 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.