exRNAdisease

Entry Detail

---



General Information

Database ID: exR0428935 RNA Name: ADGRV1 RNA Type: mRNA Chromosome: chr5 Starnd: + Coordinate: Start Site(bp): 90529344 End Site(bp): 91164437 External Links: ENSG00000164199

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand TTC37 chr5 95461755 95555007 - PODXL2 chr3 127629185 127672802 + DVL1 chr1 1335276 1349418 - RPL18A chr19 17859910 17864153 + TACO1 chr17 63600882 63608365 + CANX chr5 179678628 179731641 + MGAT1 chr5 180784782 180815652 - TMEM60 chr7 77793728 77798434 - SHROOM3 chr4 76435229 76783253 + SETD5 chr3 9397615 9479240 + TAF1 chrX 71366239 71532374 + MT-ND1 chrMT 3307 4262 + PLXNA3 chrX 154458281 154477779 + PSMD12 chr17 67337916 67366605 - NEURL4 chr17 7315628 7329393 - SNRNP40 chr1 31259568 31296788 - MTHFD2 chr2 74198610 74217565 + CTNND1 chr11 57753243 57819546 + WDR33 chr2 127701027 127811187 - OPA1 chr3 193593144 193697811 + CSNK1G1 chr15 64165525 64356173 - ORAI2 chr7 102433106 102456825 + HCN3 chr1 155277463 155289848 + TUBB chr6 30720352 30725426 + RSAD1 chr17 50478860 50485974 + FANCL chr2 58159243 58241372 - CNNM1 chr10 99329356 99394330 + PHRF1 chr11 576470 612222 + HNRNPA1L2 chr13 52642425 52643796 + PLAGL2 chr20 32192504 32207743 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC021504.1 chr18 41465783 41632185 - AC106798.1 chr5 67699429 67902600 - LINC02428 chr4 103255822 103454667 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.