exRNAdisease

Entry Detail

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General Information

Database ID: exR0428937 RNA Name: ADH5 RNA Type: mRNA Chromosome: chr4 Starnd: - Coordinate: Start Site(bp): 99070978 End Site(bp): 99088801 External Links: ENSG00000197894

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand GALNT2 chr1 230057990 230282122 + CLPTM1 chr19 44954585 44993341 + BUB1B chr15 40161023 40221136 + MAD1L1 chr7 1815793 2233243 - PSAP chr10 71816298 71851325 - RSAD1 chr17 50478860 50485974 + PTPN6 chr12 6946468 6961316 + ACTR6 chr12 100199122 100241865 + SRP68 chr17 76038775 76072517 - CEBPZ chr2 37201612 37231596 - SEC61A1 chr3 128051641 128071683 + TYRO3 chr15 41557675 41583589 + RPS19 chr19 41860255 41872925 + SMARCA4 chr19 10960825 11079426 + ILF2 chr1 153661788 153671028 - NUDCD3 chr7 44379119 44490658 - SEC22A chr3 123201927 123274136 + RAN chr12 130872037 130877678 + OTX2 chr14 56799905 56816693 - RPL15 chr3 23916545 23924374 + SLX1A chr16 30193887 30197561 + C5orf30 chr5 103258763 103278660 + TUBB chr6 30720352 30725426 + WDFY1 chr2 223855716 223945357 - AL136454.1 chr1 192716132 192716653 + VIM chr10 17228241 17237593 + TAF6 chr7 100107070 100119841 - HMGA1 chr6 34236873 34246231 + PABPC1 chr8 100685816 100722809 - VCL chr10 73995193 74121363 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-1825 chr20 32237830 32237847 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand C5orf17 chr5 23951348 24178263 + OXCT1-AS1 chr5 41869927 41872241 + SLX1A-SULT1A3 chr16 30193892 30204310 + SNHG15 chr7 44983023 44986961 - TUG1 chr22 30969245 30979395 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.