exRNAdisease

Entry Detail

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General Information

Database ID: exR0428940 RNA Name: ADI1 RNA Type: mRNA Chromosome: chr2 Starnd: - Coordinate: Start Site(bp): 3497366 End Site(bp): 3519531 External Links: ENSG00000182551

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ENO3 chr17 4948092 4957131 + GNL2 chr1 37566816 37595937 - ZNF485 chr10 43606419 43617904 + CYTH2 chr19 48469208 48482314 + APP chr21 25880550 26171128 - RPL36 chr19 5674947 5691875 + SLC44A2 chr19 10602457 10644557 + PAICS chr4 56435741 56464579 + TMSB4X chrX 12975110 12977227 + RPS14 chr5 150442635 150449739 - SERPING1 chr11 57597387 57614848 + STC2 chr5 173314713 173329503 - LIMS1 chr2 108534355 108687246 + SMARCA4 chr19 10960825 11079426 + TTLL6 chr17 48762235 48817214 - MORF4L2 chrX 103675496 103688158 - ADD3 chr10 109996368 110135565 + SLC11A2 chr12 50979401 51028566 - RWDD3 chr1 95234210 95247225 + HNRNPAB chr5 178204533 178211163 + QPRT chr16 29663279 29698699 + TCF7L1 chr2 85133392 85310387 + CIZ1 chr9 128161251 128204383 - SFSWAP chr12 131711081 131799737 + MFN1 chr3 179347709 179394936 + OCIAD1 chr4 48805212 48861817 + CCT7 chr2 73233420 73253021 + VANGL2 chr1 160400564 160428670 + U2AF1L5 chr21 6484623 6499261 - SNX3 chr6 108211222 108261246 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC009446.1 chr8 71675300 71702786 + AC022400.6 chr10 73703735 73713581 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.