exRNAdisease

Entry Detail

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General Information

Database ID: exR0428942 RNA Name: ADIPOR1 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 202940826 End Site(bp): 202958572 External Links: ENSG00000159346

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand HEATR6 chr17 60041008 60078922 - SLC25A3 chr12 98593591 98606379 + CHD8 chr14 21385194 21456126 - PMM2 chr16 8788823 8849325 + ATP6AP1 chrX 154428645 154436516 + MAP3K11 chr11 65597756 65615382 - PLSCR3 chr17 7389727 7394842 - TMED5 chr1 93149742 93180516 - HIVEP1 chr6 12008762 12164999 + HSCB chr22 28742039 28757515 + TMEM109 chr11 60914158 60923443 + PDIA4 chr7 149003062 149028662 - TUBA1B chr12 49127782 49131397 - PCNX3 chr11 65615773 65637439 + CELF1 chr11 47465933 47565569 - PLIN2 chr9 19108375 19149290 - COMMD4 chr15 75336020 75343224 + TMED3 chr15 79311112 79427432 + SC5D chr11 121292681 121313410 + TRAPPC10 chr21 44012309 44106552 + HNRNPH1 chr5 179614178 179634784 - MGAT1 chr5 180784782 180815652 - RBAK chr7 5045821 5069487 + ZC3H18 chr16 88570381 88631966 + AQR chr15 34851782 34969742 - PPIA chr7 44796680 44824564 + DOCK2 chr5 169637268 170083382 + COX7C chr5 86617928 86620962 + MARCKSL1 chr1 32333839 32336233 - NEK3 chr13 52132639 52159861 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC006064.5 chr12 6510275 6510522 + AC010733.2 chr2 60925909 60931610 + AC022167.2 chr16 8848105 8860456 + AC020915.1 chr19 58278966 58315197 + MALAT1 chr11 65497688 65506516 + NORAD chr20 36045618 36051018 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.