exRNAdisease

Entry Detail

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General Information

Database ID: exR0428943 RNA Name: ADIPOR2 RNA Type: mRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 1688574 End Site(bp): 1788674 External Links: ENSG00000006831

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand DOCK2 chr5 169637268 170083382 + HP1BP3 chr1 20740266 20787323 - MMP15 chr16 58025754 58046901 + SKA3 chr13 21153595 21176552 - MYO5A chr15 52307283 52529050 - BRD4 chr19 15235519 15332545 - DAZAP1 chr19 1407569 1435687 + EMC6 chr17 3668812 3669668 + DBNL chr7 44044640 44069456 + CAPZA2 chr7 116811070 116922049 + VPS26C chr21 37223420 37267919 - TAGLN2 chr1 159918107 159925732 - LDHA chr11 18394560 18408425 + HADH chr4 107989714 108035175 + GALNT1 chr18 35581117 35711834 + KIF3A chr5 132692628 132737638 - HELLS chr10 94501434 94613905 + EMC10 chr19 50476400 50490870 + RPRD1A chr18 35984387 36067576 - ANKRD28 chr3 15667236 15859771 - CMTM4 chr16 66614750 66696707 - AXIN1 chr16 287440 352723 - C2orf42 chr2 70149880 70248615 - HAT1 chr2 171922448 171983686 + CDCA3 chr12 6844793 6852066 - BMP2K chr4 78776342 78916372 + ANKHD1-EIF4EBP3 chr5 140401908 140549569 + XRCC5 chr2 216107464 216206303 + SF3B1 chr2 197388515 197435091 - PUM2 chr2 20248691 20352234 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-150-5p chr19 49500832 49500853 - hsa-miR-483-3p chr11 2134142 2134162 - hsa-miR-1321 chrX 85835832 85835849 + hsa-miR-4426 chr1 192716333 192716349 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005746.1 chr17 61382785 61384680 + AL031282.2 chr1 1702736 1737688 - AL139393.2 chr6 160926269 160943110 + AP001496.2 chr18 5232876 5238526 - MALAT1 chr11 65497688 65506516 + PTPRD-AS1 chr9 8858127 8864772 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.