exRNAdisease

Entry Detail

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General Information

Database ID: exR0428944 RNA Name: ADK RNA Type: mRNA Chromosome: chr10 Starnd: + Coordinate: Start Site(bp): 74151202 End Site(bp): 74709963 External Links: ENSG00000156110

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CLTC chr17 59619689 59696956 + CORO1C chr12 108645109 108731596 - BCL2L1 chr20 31664452 31723989 - C12orf57 chr12 6942978 6946003 + IFI6 chr1 27666064 27672198 - RAB11FIP3 chr16 425649 523011 + GDI2 chr10 5765223 5842132 - GRWD1 chr19 48445841 48457022 + BCKDHA chr19 41397808 41425002 + DGKZ chr11 46332905 46380554 + IGF2 chr11 2129112 2141238 - PRMT1 chr19 49675786 49689029 + GJA1 chr6 121435595 121449727 + KRT19 chr17 41523617 41528308 - HLA-DPA1 chr6 33064569 33080775 - EIF3E chr8 108201216 108435333 - INO80B-WBP1 chr2 74455088 74460884 + TRIO chr5 14143342 14532128 + MTRNR2L8 chr11 10507894 10509186 - PTPN1 chr20 50510321 50585241 + ZNF664 chr12 123971845 124015439 + MRPL35 chr2 86199355 86213790 + CCNG1 chr5 163437569 163446151 + STAU1 chr20 49113339 49188367 - NBEAL1 chr2 203014879 203226378 + HMGN3 chr6 79201245 79234738 - RPS27L chr15 63125872 63158021 - ENO1 chr1 8861000 8879190 - UBE2J2 chr1 1253909 1273885 - TMED7 chr5 115613210 115632992 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007952.4 chr17 19112000 19112636 - AC132217.1 chr11 2129121 2129964 - AD000090.1 chr19 35557956 35581954 + IGF2-AS chr11 2140501 2148666 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.